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Johnson, P.T., Lewis, G.P., Talaga, K.C., Brown, M.N., Kappel, P.J., Fisher, S.K. Anderson, D.H. and Johnson, L.V. (2003) Drusen-associated degeneration in the retina. Invest. Ophthal. Vis. Sci. 44: 4481-4488

Anderson, D.H., R.F. Mullins, G.S. Hageman, and L.V. Johnson. 2002. A role for local inflammation in the formation of drusen in the aging eye. Am J Ophthalmol. 134:411-31.

Johnson, L.V., W.P. Leitner, A.J. Rivest, M.K. Staples, M.J. Radeke, and D.H. Anderson. 2002. The Alzheimer's A beta -peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration. Proc Natl Acad Sci U S A. 99:11830-5.

Leu, S.T., S. Batni, M.J. Radeke, L.V. Johnson, D.H. Anderson, and D.O. Clegg. 2002. Drusen are Cold Spots for Proteolysis: Expression of Matrix Metalloproteinases and Their Tissue Inhibitor Proteins in Age-related Macular Degeneration. Exp Eye Res. 74:141-54.

Anderson, D.H., S. Ozaki, M. Nealon, J. Neitz, R.F. Mullins, G.S. Hageman, and L.V. Johnson. 2001. Local cellular sources of apolipoprotein E in the human retina and retinal pigmented epithelium: implications for the process of drusen formation. Am J Ophthalmol. 131:767-81.

Johnson, L.V., W.P. Leitner, M.K. Staples, and D.H. Anderson. 2001. Complement Activation and Inflammatory Processes in Drusen Formation and Age Related Macular Degeneration. Experimental Eye Research. 73:887-896.

Hageman, G.S., Luthert, P.J., Chong, N.H., Johnson, L.V., Anderson, D.H. and Mullins, R.F. 2001. An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration. Prog Retin Eye Res. 20(6) 705-732.
(Abstract)

Anderson, D.H., Ozaki, S., Nealon, M., Staples, M., Mullins, R.F., Hageman, G.S., and Johnson, L.V. Local cellular sources of apolipoprotein E in the human retina and retinal pigmented epithelium: implications for the process of drusen formation. Am J Ophthalmol 2001: 131(6): 767-81.
(Abstract)

Johnson, LV, Ozaki, S, Staples, MK, Erickson, PA, Anderson, DH. A potential role for immune complex pathogenesis in drusen formation. Exp Eye Res. 2000; 70: 441-449.
(Abstract)

Mullins RF, Russell SR, Anderson DH, Hageman GS. Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with athero-sclerosis, elastosis, amyloidosis, and dense deposit disease. FASEB J. 2000 May;14(7):835-846. PMID: 10783137
(Abstract)

Anderson DH, Hageman GS, Mullins RF, Neitz M, Neitz J, Ozaki S, Preissner KT, Johnson LV. Vitronectin gene expression in the adult human retina. Invest Ophthalmol Vis Sci. 1999 Dec;40(13):3305-15. PMID: 10586957; UI: 20052240
(Abstract)

Ozaki S, Johnson LV, Mullins RF, Hageman GS, Anderson DH. The human retina and retinal pigment epithelium are abundant sources of vitronectin mRNA. Biochem Biophys Res Commun. 1999 May 19;258(3):524-9. PMID: 10329419; UI: 99262131
(Abstract)

Hageman GS, Mullins RF, Russell SR, Johnson LV, Anderson DH. Vitronectin is a constituent of ocular drusen and the vitronectin gene is expressed in human retinal pigmented epithelial cells. FASEB J. 1999 Mar;13(3):477-84. PMID: 10064614; UI: 99164114.
(Abstract)

Marmor, MF in The Retinal Pigment Epithelium. Function and Disease. Marmor, MF and Wolfensberger, TJ (eds) Oxford University Press. pgs 3-12 (1998).


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